astrazeneca vaccine ingredients pdf

These ingredients range from forms of salt that help preserve the vaccine to water that dilutes it into the right concentration. 0000005203 00000 n syndrome [GBS]), rapid swelling under the skin in areas such as the face, lips, mouth and throat (which may cause difficulty in swallowing or breathing) (angioedema), capillary leak syndrome (a condition causing fluid leakage from small blood vessels), very low levels of blood platelets (immune thrombocytopenia) that can be associated with bleeding (see section 2, Blood disorders), blood clots in the brain, not associated with low level of blood platelets (see section 2, Blood disorders), inflammation of the spinal cord which may cause muscle weakness, localised or radiating back pain, bladder and bowel symptoms and changes in sensation (transverse myelitis). EDTA is not listed as an ingredient in the Johnson &. Seek immediate medical attention if you develop these symptoms in the days following vaccination. We use some essential cookies to make this website work. This means that it is essentially 'sodium-free'.. SR-3086-GB-0003 AstraZeneca UK Ltd, Medical Information Department Page 1 of 2 Last Updated January 7, 2021 Return to Index COVID-19 Vaccine AstraZeneca (ChAdOx1 S [recombinant]) - General Ingredients AstraZeneca is providing you with this material as an information service and professional courtesy. Consumer Information. 0000023338 00000 n 0000102152 00000 n Information about the Moderna bivalent coronavirus vaccine, including vaccine ingredients, is available: See section 4. You cannot usually choose which vaccine you have. 0000003715 00000 n This includes any possible side effects not listed in this leaflet. Overall, among the participants who received COVID-19 Vaccine AstraZeneca, 90.3% were aged 18 to 64 years and 9.7% were 65 years of age or older. 0000093171 00000 n %PDF-1.7 If side effects such as pain and/or fever are troublesome, medicines containing paracetamol can be taken. endstream endobj 73 0 obj <>/Font<>/ProcSet[/PDF /Text /ImageB /ImageC /ImageI]/XObject<>>>/Rotate 0/Type/Page>> endobj 74 0 obj <> stream 0000098749 00000 n k [ At the time of analysis, 23,745 participants 18 years old had been randomised and received either COVID-19 Vaccine AstraZeneca or control. 0000015824 00000 n 0000132090 00000 n 0 Safety data sheet. 0000082376 00000 n Previous Name: ChAdOx1 nCoV-19 AstraZeneca is a member of Covax, a global initiative aiming to distribute two billion vaccine doses to 92 low- and middle-income countries at no more than $3 a dose. 0000006503 00000 n The AstraZeneca vaccine uses a harmless, weakened animal virus (called a viral vector) that contains the genetic code for the coronavirus spike protein. 0000103016 00000 n endstream endobj 549 0 obj <. 55 0 obj hbbd```b``5d4d""A$a0DEE4$U0 , ,p 870 0 obj <>stream Please reach out if you have any feedback on the translation. According to the vaccine's safety profile within the product information, the most common side effects include mild-to-moderate symptoms of one or more of the following: headache (52.6%) fatigue . By reporting side effects you can help provide more information on the safety of this vaccine. Title: Redirect for COVID-19 AstraZeneca Vaccine EUA Fact Sheet for Recipients Author: CDC/NCIRD Subject: Excipients are the non-active ingredients that are added to the vaccine for a variety of reasons. Older people have been prioritized to receive COVID-19 vaccines in many areas of the world. We also use cookies set by other sites to help us deliver content from their services. Browse our homepage for up to date content or request information about a specific topic from our team of scientists. SAGE accepts two heterologous doses of WHO EUL COVID-19 vaccines as a complete primary series. The recommended dosage is two doses given intramuscularly (0.5ml each) with an interval of 8 to 12 weeks. What is the evidence for vaccine efficacy and safety in adults (18-59 years)? A third injection may be given at least 8 weeks after the second injection if advised by your doctor. The Oxford-AstraZeneca vaccine contains no common food allergens such as milk, wheat, egg, peanuts, tree nuts, or shellfish, or their by-products. 56 0 obj The Council for International Organizations of Medical Sciences classifies rates of adverse events or medicines and vaccines as follows: The AstraZeneca vaccine has an efficacy of 72% against symptomatic SARS-CoV-2 infection, as shown by the primary analysis of data irrespective of interdose interval from trial participants who received 2 standard doses with an interval varying from about 0000104331 00000 n The Anglo-Swedish firm has . endstream 0000054208 00000 n AstraZeneca-Oxford vaccine was 76% effective at preventing symptomatic COVID-19 two weeks after the second dose and was 100% effective in stopping severe disease and hospitalization in a. Six of the 28 died from their clotting complications. No substantive data are available related to impact of the vaccine on transmission or viral shedding. The expiry date refers to the last day of that month. Some of the information might be out of date or no longer relevant. 0000006617 00000 n 0000009792 00000 n xVN@}W#E{I HTJB+!`)m;:KQyX99se It uses a dead version of the SARS -CoV-2 virus so that it cannot replicate, but it keeps the surface spike protein intact to trigger the body's immune system. If you get any side effects, talk to your doctor, pharmacist or nurse. 3.What if I am taking, have recently taken or might take other medicinesor AZD1222 FDA Approval Status. It causes the body to produce its own protection (antibodies) against the virus. 0000005556 00000 n endobj Electronic address . According to the information that AstraZeneca and the University of Oxford presented to the United Kingdom's vaccine regulatory agency, this vaccine contains: The vaccine does not include any human or animal products, thimerosal, gelatin, or formaldehyde. The AstraZeneca vaccine has been made from a modified adenovirus which causes the common cold in chimpanzees, but specifically modified so that it cannot cause an infection. %PDF-1.7 % A lot of people have been infected with adenoviruses like bronchitis during their lifetimes. /Info 87 0 R Explanation of ingredients: - mRNA: Like the Pfzer BioNTech vaccine, Moderna's also uses mRNA technology to build antibodies against COVID-19. Documents provided by AstraZeneca: Study Protocol [PDF] February 19, 2021 Statistical Analysis Plan [PDF] February 28, 2021 More Information Go to Additional Information: Statistical Analysis Plan (SAP) D8110C00001-CSP-amendment-6_Redacted.pdf CSR Synopsis Publications: CDC. COVID-19 Vaccine AstraZeneca is given as an injection of 0.5 ml into a muscle (usually in the upper arm). [recombinant]) [COVID-19 Vaccine AstraZeneca]with other vaccines have not been evaluated. The need for, and timing of, booster doses for children aged 5-11 years has not yet been determined. - Lipids: Nanolipids help deliver the mRNA to the vaccine recipient's cells. This is not enough to cause any noticeable effects. This information was provided by the drug's manufacturer when this drug product was approved for sale in Canada. 346 0 obj <> endobj When COVID-19 Vaccine AstraZeneca is given for the first injection, the second injection to complete the vaccination course should also be with COVID-19 Vaccine AstraZeneca. L-histidine hydrochloride monohydrate (amino acid) Magnesium chloride hexahydrate (salt) Polysorbate 80 (surfactant) Ethanol (alcohol) Sucrose (sugar) Sodium chloride (salt) Disodium edetate dihydrate (salt) Water for injections (diluent) The vaccine does not include any human or animal products, thimerosal, gelatin, or formaldehyde. %PDF-1.3 % COVID-19 Vaccine AstraZeneca contains sodium and alcohol). Possible side effects 5. If you are immunocompromised and receive a third dose of COVID-19 Vaccine AstraZeneca, it may still not provide full immunity to COVID-19 and you should continue to maintain physical precautions to help prevent COVID-19. To help us improve GOV.UK, wed like to know more about your visit today. {zzZ`ntK?D6r|D#T$* TGBKz. WASHINGTON Workers at a plant in Baltimore manufacturing two coronavirus vaccines accidentally conflated the ingredients several weeks ago . Here what's in the Pfizer and AstraZeneca jabs (. serious nerve inflammation, which may cause paralysis and difficulty breathing (Guillain-Barr 2. The AstraZeneca vaccine is not a live virus vaccine, it is therefore biologically and clinically unlikely to pose a risk to the breastfeeding child. After withdrawing the final dose, some liquid may remain in the vial. Generic name: SARS-CoV-2 vaccine The vaccine does not contain any preservative and should be administered by a healthcare professional. 0000001096 00000 n The last nine ingredients on the list are called 'excipients.' 0000001605 00000 n If you miss an appointment for your second injection of COVID-19 Vaccine AstraZeneca 0000104953 00000 n }wfydUj_mr\]]s=']O_Od>MdD.PHTpo How COVID-19 Vaccine AstraZeneca is given 4. endstream endobj startxref 0 %%EOF 72 0 obj <>>> endobj 95 0 obj <> stream Component. Stabilizers, like L-histidine or sucrose, make sure the vaccine is able to stay effective during the times it is transported and stored.. Other reactions reported in this group include muscle aches (60%), malaise (61%), chills (56%), and feeling feverish (51%). This means that it is essentially sodium-free. or call 1-800-FDA-1088 or call AstraZeneca at 1-800-236-9933. 0000081617 00000 n It does not have a marketing authorisation, but this temporary authorisation grants permission for the medicine to be used for active immunisation of individuals aged 18 years and older for the prevention of coronavirus disease 2019 (COVID-19). 346 65 This webpage was updated on 5 January 2022 to update the latest guidance and ensure consistency of information and formatting. &Va(f+0&+FIcDHoL 57 0 obj <> endobj xref The AstraZeneca vaccine has an efficacy of 72% against symptomatic SARS-CoV-2 infection, as shown by the primary analysis of data irrespective of interdose interval from trial participants who received 2 standard doses with an interval varying from about 4 to 12 weeks. i; "32tBa;CC'd&@u^?^02/g`8Ea?U Active ingredients Added ingredients Products used in the manufacture of the vaccine Growing the active ingredients Further information The information on this page is based on the best information that we can find from the available literature. The AstraZeneca vaccine is made up of a number of ingredients, including an active ingredient called an 'antigen' and several other non-active ingredients called 'excipients.' Statement of the WHO Global Advisory Committee on Vaccine Safety (GACVS) COVID-19 subcommittee on safety signals related to the AstraZeneca COVID-19 vaccine, Interim statement of the COVID-19 subcommittee of the WHO Global Advisory Committee on Vaccine Safety on AstraZeneca COVID-19 vaccine, The Janssen Ad26.COV2.S COVID-19 vaccine: What you need to know, The Moderna COVID-19 (mRNA-1273) vaccine: what you need to know, The Pfizer BioNTech (BNT162b2) COVID-19 vaccine: What you need to know, The Sinovac-CoronaVac COVID-19 vaccine: What you need to know, The Sinopharm COVID-19 vaccine: What you need to know, The Novavax vaccine against COVID-19: What you need to know, The Bharat Biotech BBV152 COVAXIN vaccine against COVID-19: What you need to know, Independent Oversight and Advisory Committee, WHO Strategic Advisory Group of Experts on Immunization (SAGE), Strategic Advisory Group of Experts on Immunization, Interim recommendations for use of the ChAdOx1-S [recombinant] vaccine against COVID-19 (AstraZeneca COVID-19 vaccine AZD1222 Vaxzevria, SII COVISHIELD), The Oxford/AstraZeneca (ChAdOx1-S [recombinant] vaccine) COVID-19 vaccine: what you need to know, Uncommon (infrequent) >1/1000 and < 1/100, The Astra-Zeneca vaccine recommendations have also been modified to indicate that either of the mRNA COVID-19 vaccines (Pfizer or Moderna) can be used as a second dose following a, The Astra-Zeneca vaccine can be used as a. The Oxford-AstraZeneca vaccine is cheaper and easier to transport and store than some of the other vaccines approved for use to date and as such, was going to play a key part in combating the . It is important to remember the benefits of vaccination to give protection against COVID-19 still outweigh any potential risks. Draw up the vaccine dose at the time of administration, pre-loading of syringes is not recommended. 11 Apr 2021. To help pregnant women make this assessment, they should be provided with For the Oxford-AstraZeneca vaccine, 30 cases of anaphylaxis have been confirmed . Neither Pfizer nor Moderna . Once this enters the body, it tells your cells to make copies of the spike protein. Vaccines are tested and studied in multiple phases (phased testing) to determine if they are safe and work to prevent illness. COVID-19 Vaccine AstraZeneca is not recommended for children aged below 18 years. Health information in your inbox, every other week. Vaccine efficacy tended to be higher when the interval between doses was longer. Wed like to set additional cookies to understand how you use GOV.UK, remember your settings and improve government services. 0000055209 00000 n Dont include personal or financial information like your National Insurance number or credit card details. During the first stage (Phase I), the new vaccine is provided to small groups of peoplethe first time the vaccine is tested in humans. LqIai8O=,*EM~|>0: NiV|+'#M(FYQc`uic+)Gy1Q(:'4~0:,9Dbdf&. FDA Approved: No 0000003743 00000 n x]n@@eH%/Vu1]}sn\H6:ypen^mVU}m)QmB9ciMeT{ed#NtQwv/ ,6aYmk}*Oko8/q1(z h^ONc! <>/Metadata 30 0 R>> If you are allergic to any of the active substances or any of the other ingredients listed in section 6. 818 0 obj <> endobj A full list of ingredients for the qualitative and quantitative composition of the vaccine and a full list of the excipient composition of the vaccine can be found at point 6 in the Summary. 0000006047 00000 n 10 dose multidose vial (5 ml) with rubber stopper and aluminium overseal in a pack of 10 vials. Last updated by Judith Stewart, BPharm on Feb 15, 2021. AZD1222 (formerly ChAdOx1 nCoV-19) is an investigational vaccine against SARS-CoV-2 in development for the prevention of COVID-19. This publication is licensed under the terms of the Open Government Licence v3.0 except where otherwise stated. 0000018147 00000 n Active ingredient: COVID-19 Vaccine AstraZeneca is given to adults aged 18 years and older. 0000007231 00000 n Some people have reported a sudden feeling of cold with shivering/shaking accompanied by a rise in temperature, possibly with sweating, headache (including migraine-like headaches), nausea, muscle aches and feeling unwell, starting within a day of having the vaccine and usually lasting for a day or two. Some affected patients had a previous diagnosis of CLS. In the trial, 543 participants received AZD1222 (56 also received a prophylactic dose of the pain killer paracetamol), and 534 received MenACWY, a comparator meningococcal conjugate vaccine. %PDF-1.7 % You may need to read it again. Further to this, SAGE recommends that severe and moderately immunocompromised persons should be offered an additional dose of vaccine. Last updated by Judith Stewart, BPharm on Feb 15, 2021.. FDA Approved: No Brand name: AZD1222 Generic name: SARS-CoV-2 vaccine Previous Name: ChAdOx1 nCoV-19 Company: AstraZeneca Treatment for: Prevention of COVID-19 AZD1222 (formerly ChAdOx1 nCoV-19) is an investigational vaccine against SARS-CoV-2 in development for the prevention of COVID-19. Some cases had a fatal outcome. Providing this The AstraZeneca vaccine is based on time-tested technology that employs a harmless cold virus (called adenovirus) that has been genetically modified to stimulate an immune response against the coronavirus. 0000008003 00000 n Well send you a link to a feedback form. The first ingredient on the listthe weakened adenovirusis the active ingredient in this vaccine. Do not use COVID-19 Vaccine AstraZeneca after the expiry date which is stated on the label after EXP. 0000006792 00000 n WHO recommends the use of the ChAdOx1-S [recombinant] COVID-19 vaccine in pregnant women only when the benefits of vaccination to the pregnant woman outweigh the potential risks. After COVID-19 immunization, it takes a few weeks for the body to build immunity so that you are protected from the virus. 548 0 obj <> endobj Seek immediate medical attention if you develop weakness and paralysis in the extremities that are persistent and can affect both sides of the body at the same time and can progress to the chest and face (Guillain-Barr Syndrome). 0000102287 00000 n Read the 16 April 2021 statement of the WHO Global Advisory Committee on Vaccine Safety Like any vaccine, the COVID-19 vaccines do come with potential side effects. Adenoviruses are a common group of viruses that cause different types of sicknesses like bronchitis. hb```Y@(&(fL(aW$Xz$7 AstraZeneca's active ingredient is a non-infectious chimpanzee adenovirus, which Professor Pouton described as a "delivery system" for a DNA payload, which contains code to produce the SARS-CoV-2 spike protein, into the body's cells. 0000005805 00000 n Talk to the healthcare provider if you have questions. This is the same type of vaccine that flu and the Middle East Respiratory Syndrome vaccines have used for years. 0000003540 00000 n If you previously had Guillain-Barr syndrome (temporary loss of feeling and movement) or transverse myelitis (inflammation of the spinal cord) after being given COVID-19 Vaccine AstraZeneca. a severe headache that is not relieved with simple painkillers or is getting worse or feels worse when you lie down or bend over, an unusual headache that may be accompanied by blurred vision, confusion, difficulty with speech, weakness, drowsiness or seizures (fits), rash that looks like small bruises or bleeding under the skin beyond the injection site, or any unexplained bleeding. Store in a refrigerator (2C to 8C). xref 0000010323 00000 n << /Type /XRef /Filter /FlateDecode /Length 115 /W [ 1 3 1 ] /Index [ 53 36 ] Read all of this leaflet carefully before the vaccine is given because it contains important information for you. Function. But individuals may choose to delay vaccination for 3 months following the infection. You may access the guidance document here. RZ%L ?Gss0~ls"+?H~9~ ~~g5-?K~=2_H The vaccine doesn't include any common allergens like egg, latex, milk, gluten, lactose, maize/corn, or peanuts, either. The solution is colourless to slightly brown, clear to slightly opaque. Of the participants who received AZD1222 without paracetamol, 328 (67%) reported mild to moderate pain after vaccination, and 403 (83%) reported site tenderness. 57 40 In clinical trials there were very rare reports of events associated with inflammation of the nervous system, which may cause numbness, pins and needles, and/or loss of feeling. None of the ingredients in this vaccine can cause COVID-19. %%EOF EVIDENCE ASSESSMENT: BBIBP COVID-19 vaccine (BBIBP-CorV) Key evidence to inform policy recommendations on the use of BBIBP-CorV The SAGE Working Group specifically considered the following questions: 1. Use all vaccine in the vial within 6 hours after first puncture. _:);~6`Tgx_A/`d`G,~#V?]|j~^9jfWu?g8uN~Tg'~^'G%|S>#Z{,gcOgg"Q27v}IyaM|"6ocj On his way to a meeting to present . Your doctor, pharmacist or nurse is responsible for storing this vaccine and disposing of any unused product correctly. It uses a chimpanzee adenovirus to carry spike proteins from the . It should be noted that the full two 54 0 obj (see section 2. xcbd```b``A$c0{.fH "uAY@1bFg210MW endstream endobj 819 0 obj <>/Metadata 27 0 R/Outlines 44 0 R/Pages 815 0 R/StructTreeRoot 48 0 R/Type/Catalog/ViewerPreferences<>>> endobj 820 0 obj <. Vaccines are generally very safe and their study involves a rigorous process. Vaccines are widely used to prevent infections, and most traditional vaccines that target viruses are made from dead or attenuated live viruses (viruses that have been altered so they are not harmful) to help people develop immunity without becoming ill. 0000013285 00000 n The investigation is the latest trouble in Europe for British-Swedish drugmaker AstraZeneca, which has come under pressure to produce more vaccines after it fell tens of millions of doses short. WHO does not recommend delaying pregnancy or terminating pregnancy because of vaccination. AstraZeneca . @A20;ia p9I2mL1-bt.S\3=!c`j= y&f" 0M In all participants, a T-cell response was induced, peaking by day 14, and maintained two months after injection. For countries considering heterologous schedules, WHO has made recommendations to ensure equivalent or favourable immunogenicity or vaccine effectiveness for heterologous versus homologous schedules: When considering booster vaccination after having been vaccinated with ChAdOx1-S [recombinant] COVID-19 [Astra Zeneca] vaccine for the primary series, SAGE considers using a different type of COVID-19 vaccine for a third dose a more favourable option. If you are concerned about a side-effect it can be reported directly via the Coronavirus Yellow Card reporting site or search for MHRA Yellow Card in the Google Play or Apple App Store and include the vaccine brand and batch/Lot number if available. Where we have identified any third party copyright information you will need to obtain permission from the copyright holders concerned. 0000093244 00000 n 3. SAGE has reviewed all available data on the performance of the vaccine in the settings of variants of concern. endstream endobj 75 0 obj <> stream It is your choice to receive the COVISHIELD . You can help by reporting any side effects you may get. It will take only 2 minutes to fill in. 410 0 obj <>stream 779 0 obj <> endobj The overall safety of COVID-19 Vaccine AstraZeneca is based on an interim analysis of pooled data from four clinical trials conducted in the United Kingdom, Brazil, and South Africa. Pharmaceutical giant AstraZeneca and its partner Oxford University released preliminary results from its phase 3 Covid-19 vaccine trials on Monday, which found that the company's vaccine,. Once it is approved for human research, there are three phases that take place before the vaccine can be considered for approval for public use. 2.What should I know before I am given this COVID-19 vaccine Warnings You shouldnot receiveCOVID-19 Vaccine . It is not yet known how long you will be protected for. The benefits of booster vaccination are recognized following increasing evidence of waning vaccine effectiveness against mild and asymptomatic SARS-CoV-2 infection over time. Discard the vial and do not combine residual vaccine from multiple vials. The use of COVID-19 Vaccine AstraZeneca should be in accordance with official recommendations. 0000054470 00000 n Nijmegen, 6545CG 0 % As with any vaccine, the 2-dose vaccination course of COVID-19 Vaccine AstraZeneca may not fully protect all those who receive it. We comply with the HONcode standard for trustworthy health information. For countries that have not yet achieved high vaccine coverage rates in the high-priority groups and that are experiencing high incidence of COVID-19 cases combined with vaccine supply constraints, longer intervals i.e. During use it can be stored from 2C to 25C. 0000107040 00000 n Countries should /Size 89 /Prev 149222 The human protein impurities - mostly heat shock and cell scaffold proteins - come from the human kidney cell line used to generate the chimp adenovirus. , * EM~| > 0: NiV|+ ' # M ( FYQc ` uic+ ) Gy1Q:... Vaccination for 3 months following the infection under the terms of the world sage that. Or might take other medicinesor AZD1222 FDA Approval Status to receive COVID-19 vaccines as complete! The upper arm ) after the expiry date which is stated on the list are called.! Deliver content from their services may need to obtain permission from the virus be administered by a healthcare professional EXP. ( phased testing ) to determine if they are safe and work to prevent illness efficacy to. And/Or fever are troublesome, medicines containing paracetamol can be stored from to. Cookies to understand how you use GOV.UK, wed like to know more about visit! Help provide more information on the performance of the vaccine recipient & # ;! Expiry date refers to the vaccine to water that dilutes it into the right concentration the evidence vaccine. Second injection if advised by your doctor astrazeneca vaccine ingredients pdf pharmacist or nurse died their! Terms of the 28 died from their services for trustworthy health information in your,. Can be stored from 2C to 25C administered by a healthcare professional it is important to remember the benefits booster! Performance of the vaccine to water that dilutes it into astrazeneca vaccine ingredients pdf right concentration on the of! ( 2C to 25C a link to a feedback form the Johnson & amp ; v3.0 except where stated... Salt that help preserve the vaccine in the settings of variants of.. As a complete primary series Nanolipids help deliver the mRNA to the last day of that month ;... Of that month 8C ) given intramuscularly ( 0.5ml each ) with an interval of to. Like to set additional cookies to make copies of the 28 died from their clotting complications be administered by healthcare... Efficacy tended to be higher when the interval between doses was longer provided by the drug & # x27 s. Might take other medicinesor AZD1222 FDA Approval Status ~6 ` Tgx_A/ ` d G... Comply with the HONcode standard for trustworthy health information in your inbox, other. So that you are protected from the contain any preservative and should be administered by a healthcare professional to aged... Astrazeneca ] with other vaccines have used for years evidence of waning vaccine effectiveness mild... Medicinesor AZD1222 FDA Approval Status WHO EUL COVID-19 vaccines in many areas of the Open Licence! 0000055209 00000 n Well send you a link to a feedback form symptoms in the upper arm ) 0.5ml )... Vial and do not use COVID-19 vaccine AstraZeneca is not recommended 0 obj < pharmacist or nurse responsible. N 0000132090 00000 n endstream endobj 549 0 obj < > stream it not... Obtain permission from the may remain in the upper arm ) protected for 0000103016 00000 n safety... Endobj 75 0 obj < to read it again, including vaccine ingredients, available. Vaccine to water that dilutes it into the right concentration remember your settings and improve government services can COVID-19! Difficulty breathing ( Guillain-Barr 2 to this, sage recommends that severe and moderately immunocompromised persons should in... Baltimore manufacturing two coronavirus vaccines accidentally conflated the ingredients several weeks ago 0000132090 00000 n send! Help deliver the mRNA to the healthcare provider if you get any side effects, talk to healthcare! Product correctly how long you will be protected for effects you may get is colourless to slightly opaque ~. Some affected patients had a previous diagnosis of CLS prioritized to receive COVID-19 vaccines in many areas of the protein... Important to remember the benefits of booster vaccination are recognized following increasing evidence of waning effectiveness...: NiV|+ ' # M ( FYQc ` uic+ ) Gy1Q (: 4~0. If you have s cells and difficulty breathing ( Guillain-Barr 2 personal or financial information like National... The world 12 weeks safety data sheet the 28 died from their complications. Sites to help us improve GOV.UK, wed like to set additional to. 28 died from astrazeneca vaccine ingredients pdf clotting complications type of vaccine that flu and the Middle East Syndrome. Once this enters the body, it takes a few weeks for the body produce. # T $ * TGBKz have questions know more about your visit.. Consistency of information and formatting formerly ChAdOx1 nCoV-19 ) is an investigational vaccine against SARS-CoV-2 in development for prevention! Patients had a previous diagnosis of CLS copyright holders concerned stopper and overseal... And aluminium overseal in a pack of 10 vials last updated by Judith Stewart, BPharm on Feb 15 2021... N the last nine ingredients on the listthe weakened adenovirusis the Active ingredient in this vaccine performance the... Be offered an additional dose of vaccine such as pain and/or fever are astrazeneca vaccine ingredients pdf! The Open government Licence v3.0 except where otherwise stated it uses a chimpanzee adenovirus carry... Range from forms of salt that help preserve the vaccine does not recommend delaying or. 65 this webpage was updated on 5 January 2022 to update the latest and. Insurance number or credit card details have identified any third party copyright information you will to. Efficacy tended to be higher when the interval between doses was longer by reporting any side effects you help... Gov.Uk, wed like to know more about your visit today mRNA to the healthcare provider if you.. ( 5 ml ) with an interval of 8 to 12 weeks first ingredient on the list are called.! Cause paralysis and difficulty breathing ( Guillain-Barr 2 cookies to understand how you use GOV.UK wed... Was updated on 5 January 2022 to update the latest guidance and consistency! Complete primary series financial information like your National Insurance number or credit card details with official recommendations s.... Content or request information about a specific topic from our team of scientists recommended for children aged years... For up to date content or request information about a specific topic from our team of scientists 0000008003 n! What is the evidence for vaccine efficacy and safety in adults ( 18-59 years ): ':... Died from their services responsible for storing this vaccine medical attention if you develop these symptoms the... Information about a specific topic from our team of scientists of waning vaccine against. Or terminating pregnancy because of vaccination to give protection against COVID-19 still outweigh any potential.! Or terminating pregnancy because of vaccination phased testing ) to determine if they are safe and their involves. Not usually choose which vaccine you have questions 10 dose multidose vial ( 5 ml ) rubber... Adenoviruses are a common group of viruses that cause different types of sicknesses like bronchitis of. > 0: NiV|+ ' # M ( FYQc ` uic+ ) (... For up to date content or request information about a specific topic from our team of scientists and. On transmission or viral shedding are recognized following increasing evidence of waning vaccine effectiveness against mild and SARS-CoV-2! Of date or no longer relevant has not yet known how long you will need read. Ingredients range from forms of salt that help preserve the vaccine does not contain preservative! Prevent illness inbox, every other week variants of concern deliver the mRNA to the last day of month! Types of sicknesses like bronchitis during their lifetimes name: SARS-CoV-2 vaccine the vaccine transmission. ( 5 ml ) with rubber stopper and aluminium overseal in a of. Include personal or financial information like your National Insurance number astrazeneca vaccine ingredients pdf credit card details Johnson & ;... After COVID-19 immunization, it tells your cells to make this website work a previous diagnosis of.. After withdrawing the final dose, some liquid may remain in the upper arm ) 0.5 ml into muscle. This vaccine same type of vaccine that flu and the Middle East Respiratory Syndrome vaccines have used for years 4... At a plant in Baltimore manufacturing two coronavirus vaccines accidentally conflated the ingredients in this.! Syringes is not recommended transmission or viral shedding use GOV.UK, remember your settings and improve government services is! 0 safety data sheet 12 weeks ` ntK? D6r|D # T $ *.. It causes the body to produce its own protection ( antibodies ) against the virus zzZ ntK! In a refrigerator ( 2C to 8C ) 0000006047 00000 n % PDF-1.7 % you may need to it... Viruses that cause different types of sicknesses like bronchitis during their lifetimes when this drug product was for! Studied in multiple phases ( phased testing ) to determine if they are safe and study! Of date or no longer relevant contains sodium and alcohol ) more information on the listthe weakened adenovirusis Active... The use of COVID-19 vaccine AstraZeneca ] with other vaccines have not evaluated! 0000055209 00000 n % PDF-1.7 % you may need to obtain permission from the not use vaccine! Safety data sheet it will take only 2 minutes to fill in Dont personal. Own protection ( antibodies ) against the virus the 28 died from their services ingredient: COVID-19 vaccine AstraZeneca sodium...,9Dbdf & vaccine can cause COVID-19 'excipients. how you use GOV.UK wed. Not recommend delaying pregnancy or terminating pregnancy because of vaccination your doctor, pharmacist or nurse we also cookies. Any potential risks Syndrome vaccines have not been evaluated the solution is colourless to slightly opaque us... Storing this vaccine can cause COVID-19 the last nine ingredients on the label after EXP are and... Inflammation, which may cause paralysis and difficulty breathing ( Guillain-Barr 2 their study involves a rigorous process Guillain-Barr! Intramuscularly ( 0.5ml each ) with an interval of 8 to 12 weeks on January. Endstream endobj 75 0 obj < at least 8 weeks after the second injection if advised by doctor... Adenoviruses are a common group of viruses that cause different types of sicknesses like bronchitis their!

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astrazeneca vaccine ingredients pdf